nlmixr: Nonlinear Mixed Effects Models in Population PK/PD

Fit and compare nonlinear mixed-effects models in differential equations with flexible dosing information commonly seen in pharmacokinetics and pharmacodynamics (Almquist, Leander, and Jirstrand 2015 <doi:10.1007/s10928-015-9409-1>). Differential equation solving is by compiled C code provided in the 'RxODE' package (Wang, Hallow, and James 2015 <doi:10.1002/psp4.12052>).

Getting started

Package details

AuthorMatthew Fidler [aut] (<>), Yuan Xiong [aut], Rik Schoemaker [aut] (<>), Justin Wilkins [aut] (<>), Wenping Wang [aut, cre], Robert Leary [ctb], Mason McComb [aut] (<>), Vipul Mann [aut], Mirjam Trame [ctb], Teun Post [ctb], Richard Hooijmaijers [aut], Hadley Wickham [ctb], Dirk Eddelbuettel [cph], Johannes Pfeifer [ctb], Robert B. Schnabel [ctb], Elizabeth Eskow [ctb], Emmanuelle Comets [ctb], Audrey Lavenu [ctb], Marc Lavielle [ctb], David Ardia [cph], Katharine Mullen [cph], Ben Goodrich [ctb]
MaintainerWenping Wang <>
LicenseGPL (>= 2)
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:

Try the nlmixr package in your browser

Any scripts or data that you put into this service are public.

nlmixr documentation built on March 27, 2022, 5:05 p.m.