nlmixr: Nonlinear Mixed Effects Models in Population PK/PD

Fit and compare nonlinear mixed-effects models in differential equations with flexible dosing information commonly seen in pharmacokinetics and pharmacodynamics (Almquist, Leander, and Jirstrand 2015 <doi:10.1007/s10928-015-9409-1>). Differential equation solving is by compiled C code provided in the 'RxODE' package (Wang, Hallow, and James 2015 <doi:10.1002/psp4.12052>).

Getting started

Package details

AuthorMatthew Fidler [aut] (<https://orcid.org/0000-0001-8538-6691>), Yuan Xiong [aut], Rik Schoemaker [aut] (<https://orcid.org/0000-0002-7538-3005>), Justin Wilkins [aut] (<https://orcid.org/0000-0002-7099-9396>), Wenping Wang [aut, cre], Robert Leary [ctb], Mason McComb [aut] (<https://orcid.org/0000-0001-9871-8616>), Mirjam Trame [ctb], Teun Post [ctb], Richard Hooijmaijers [aut], Hadley Wickham [ctb], Dirk Eddelbuettel [cph], Johannes Pfeifer [ctb], Robert B. Schnabel [ctb], Elizabeth Eskow [ctb], Emmanuelle Comets [ctb], Audrey Lavenu [ctb], Marc Lavielle [ctb], David Ardia [cph], Daniel C. Dillon [ctb], Katharine Mullen [cph], Ben Goodrich [ctb]
MaintainerWenping Wang <wwang8198@gmail.com>
LicenseGPL (>= 2)
Version2.0.4
URL https://github.com/nlmixrdevelopment/nlmixr
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("nlmixr")

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nlmixr documentation built on April 17, 2021, 5:12 p.m.