nlmixr: Nonlinear Mixed Effects Models in Population Pharmacokinetics and Pharmacodynamics

Fit and compare nonlinear mixed-effects models in differential equations with flexible dosing information commonly seen in pharmacokinetics and pharmacodynamics (Almquist, Leander, and Jirstrand 2015 <doi:10.1007/s10928-015-9409-1>). Differential equation solving is by compiled C code provided in the 'RxODE' package (Wang, Hallow, and James 2015 <doi:10.1002/psp4.12052>).

Package details

AuthorMatthew Fidler [aut], Yuan Xiong [aut], Rik Schoemaker [aut], Justin Wilkins [aut], Mirjam Trame [aut], Teun Post [aut], Robert Leary [ctb], Wenping Wang [aut, cre], Hadley Wickham [ctb], Dirk Eddelbuettel [cph], David Ardia [cph], Katharine Mullen [cph]
MaintainerWenping Wang <[email protected]>
LicenseGPL (>= 2)
Package repositoryView on CRAN
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nlmixr documentation built on Sept. 23, 2018, 5:04 p.m.