neonatal_wt: Neonatal weight progression data

In nlmixr2data: Nonlinear Mixed Effects Models in Population PK/PD, Data

Neonatal weight progression data

Description

Longitudinal body-weight measurements for a cohort of neonates over roughly the first week of life, used as the second case study (neonatal weight progression) in Rohleff et al. (2025) on VAE-based nonlinear mixed-effects modeling. There is no dosing; body weight follows a turnover (zero-order production, first-order elimination) growth model whose initial weight is an estimated parameter, so every record is an observation (EVID = 0).

Usage

neonatal_wt

Format

A data frame with 1120 rows by 9 columns

ID

Subject ID (189 neonates)

TIME

Time since birth (days)

DV

Dependent Variable, body weight (g)

EVID

rxode2/nlmixr2 event ID (0 = observation; no dosing)

Sex

Sex, 0/1

DelM

Delivery mode, 0/1

GA

Gestational age at birth (weeks)

Mage

Maternal age (years)

Para2

Parity indicator, 0/1

Source

Rohleff et al. (2025), CPT: Pharmacometrics & Systems Pharmacology

See Also

Other nlmixr2 datasets: Bolus_1CPT, Bolus_1CPTMM, Bolus_2CPT, Bolus_2CPTMM, Infusion_1CPT, Infusion_1CPTMM, Infusion_2CPT, Infusion_2CPTMM, Oral_1CPT, Oral_1CPTMM, Oral_2CPT, Oral_2CPTMM, Wang2007, mavoglurant, nimoData, nmtest, pheno_sd, rats, theo_md, theo_sd, warfarin, wbcSim

nlmixr2data documentation built on July 10, 2026, 5:07 p.m.