In bulk epigenome/transcriptome experiments, molecular expression is measured in a tissue, which is a mixture of multiple types of cells. This package tests association of a disease/phenotype with a molecular marker for each cell type. The proportion of cell types in each sample needs to be given as input. The package is applicable to epigenome-wide association study (EWAS) and differential gene expression analysis. Takeuchi and Kato (submitted) "omicwas: cell-type-specific epigenome-wide and transcriptome association study".
Package details |
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Author | Fumihiko Takeuchi [aut, cre] (<https://orcid.org/0000-0003-3185-5661>) |
Maintainer | Fumihiko Takeuchi <fumihiko@takeuchi.name> |
License | GPL-3 |
Version | 0.8.0 |
URL | https://github.com/fumi-github/omicwas |
Package repository | View on CRAN |
Installation |
Install the latest version of this package by entering the following in R:
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