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### Function used for estimating profile likelihood confidence intervals hybrid
# method
get_profile_ci <- function(x, es, n_bs, par_fixed, mods, est, tau2, ind,
chi_cv, ll)
{
par_fixed[ind] <- x
### Remove the fixed parameters from par
par_transf <- c(est, log(tau2))[is.na(par_fixed) == TRUE]
### Re-estimate model without the fixed parameter. Multiply with -1 to
# get the log-likelihood, because ml_mods() returns the negative log-likelihood
if (length(par_transf) == 1)
{ # If only one parameter is estimated, use optimize() instead of optim()
ll0 <- -1*optimize(ml_hy, interval = c(-10,10), es = es, mods = mods,
n_bs = n_bs, par_fixed = par_fixed, transf = TRUE,
verbose = FALSE)$objective
} else
{
ll0 <- -1*optim(par = par_transf, fn = ml_hy, method = "Nelder-Mead",
es = es, mods = mods, n_bs = n_bs, par_fixed = par_fixed,
transf = TRUE, verbose = FALSE)$value
}
return(-2*(ll0-ll)-chi_cv)
}
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