Data on ovariole number in a backcross between D. simulans and D. sechellia; the majority of individuals were selected to be recombinant in the region of a putative QTL on chromosome 3.
An object of class
The data come from an interspecific Drosophila backcross. D. simulans was crossed to D. sechellia, and the F1 hybrid was crossed back to D. simulans.
The phenotype of interest was ovariole number in females (a measure of
on2 are the ovariole counts in
the left and right gonads. The phenotype
onm is the average of the
two counts; for many individuals, the ovariole count for one of two gonads
was missing, and so
onm is missing.
In an initial cross of 402 individuals, 383 had complete phenotype data. Initial genotyping focused on 94 individuals with extreme phenotype.
To increase the resolution of a major QTL identified on chromosome 3, a second cross of approximately 7000 flies was performed, though only 1050 individuals showing a recombination event between two morphological markers, st (bright red eyes) and e (dark brown body), were phenotyped and genotyped; 1038 had complete phenotype data. The aim was to oversample recombinants of the region of the QTL.
There are genotype data for 24 markers on 3 chromosomes. (The fourth chromosome had one marker, but showed no effect and is not included in these data.)
cross indicates whether an individual came from the
first or second cross.
"E" refer to D. simulans and D.
Virginie Orgogozo, Department of Ecology and Evolutionary Biology, Princeton University, firstname.lastname@example.org
Orgogozo, V., Broman, K. W. and Stern, D. L. (2006) High-resolution QTL mapping reveals sign epistasis controlling ovariole number between two Drosophila species. Genetics 173, 197–205.
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