rpact: Confirmatory Adaptive Clinical Trial Design and Analysis

Design and analysis of confirmatory adaptive clinical trials with continuous, binary, and survival endpoints according to the methods described in the monograph by Wassmer and Brannath (2016) <doi:10.1007/978-3-319-32562-0>. This includes classical group sequential as well as multi-stage adaptive hypotheses tests that are based on the combination testing principle.

Package details

AuthorGernot Wassmer [aut] (<https://orcid.org/0000-0001-9397-1794>), Friedrich Pahlke [aut, cre] (<https://orcid.org/0000-0003-2105-2582>), Till Jensen [ctb], Daniel Sabanes Bove [ctb] (<https://orcid.org/0000-0002-0176-9239>), Stephen Schueuerhuis [ctb] (<https://orcid.org/0009-0006-3124-6056>), Tobias Muetze [ctb] (<https://orcid.org/0000-0002-4111-1941>)
MaintainerFriedrich Pahlke <friedrich.pahlke@rpact.com>
LicenseLGPL-3
Version4.2.0
URL https://www.rpact.org https://www.rpact.com https://github.com/rpact-com/rpact https://rpact-com.github.io/rpact/ https://rpact.shinyapps.io/connect
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("rpact")

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rpact documentation built on April 3, 2025, 8:01 p.m.