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Design and analysis of confirmatory adaptive clinical trials with continuous, binary, and survival endpoints according to the methods described in the monograph by Wassmer and Brannath (2016) <doi:10.1007/978-3-319-32562-0>. This includes classical group sequential as well as multi-stage adaptive hypotheses tests that are based on the combination testing principle.
Package details |
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Author | Gernot Wassmer [aut] (<https://orcid.org/0000-0001-9397-1794>), Friedrich Pahlke [aut, cre] (<https://orcid.org/0000-0003-2105-2582>), Till Jensen [ctb], Stephen Schueuerhuis [ctb], Tobias Muetze [ctb] (<https://orcid.org/0000-0002-4111-1941>) |
Maintainer | Friedrich Pahlke <friedrich.pahlke@rpact.com> |
License | LGPL-3 |
Version | 4.1.0 |
URL | https://www.rpact.org https://www.rpact.com https://github.com/rpact-com/rpact https://rpact-com.github.io/rpact/ |
Package repository | View on CRAN |
Installation |
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