EventProbabilities: Event Probabilities
In rpact: Confirmatory Adaptive Clinical Trial Design and Analysis

EventProbabilities

R Documentation

Event Probabilities

Description

Class for the definition of event probabilities.

Details

EventProbabilities is a class for the definition of event probabilities.

Fields

time: The time values. Is a numeric vector.
accrualTime: The assumed accrual time intervals for the study. Is a numeric vector.
accrualIntensity: The absolute accrual intensities. Is a numeric vector of length kMax.
kappa: The shape of the Weibull distribution if kappa!=1. Is a numeric vector of length 1.
piecewiseSurvivalTime: The time intervals for the piecewise definition of the exponential survival time cumulative distribution function. Is a numeric vector.
lambda1: The assumed hazard rate in the treatment group. Is a numeric vector of length kMax.
lambda2: The assumed hazard rate in the reference group. Is a numeric vector of length 1.
allocationRatioPlanned: The planned allocation ratio (n1 / n2) for the groups. For multi-arm designs, it is the allocation ratio relating the active arm(s) to the control. Is a positive numeric vector of length 1.
hazardRatio: The hazard ratios under consideration. Is a numeric vector of length kMax.
dropoutRate1: The assumed drop-out rate in the treatment group. Is a numeric vector of length 1 containing a value between 0 and 1.
dropoutRate2: The assumed drop-out rate in the control group. Is a numeric vector of length 1 containing a value between 0 and 1.
dropoutTime: The assumed time for drop-out rates in the control and treatment group. Is a numeric vector of length 1.
maxNumberOfSubjects: The maximum number of subjects for power calculations. Is a numeric vector.
overallEventProbabilities: Deprecated field which will be removed in one of the next releases. Use cumulativeEventProbabilities instead.
cumulativeEventProbabilities: The cumulative event probabilities in survival designs. Is a numeric vector.
eventProbabilities1: The event probabilities in treatment group 1. Is a numeric vector.
eventProbabilities2: The event probabilities in treatment group 2. Is a numeric vector.