R implementation of generalized survival models, where g(S(tx))=eta(t,x) for a link function g, survival S at time t with covariates x and a linear predictor eta(t,x). The main assumption is that the time effect(s) are smooth. For fully parametric models with natural splines, this reimplements Stata's 'stpm2' function, which are flexible parametric survival models developed by Royston and colleagues. We have extended the parametric models to include any smooth parametric smoothers for time. We have also extended the model to include any smooth penalized smoothers from the 'mgcv' package, using penalized likelihood. These models include left truncation, right censoring, interval censoring, gamma frailties and normal random effects. This also includes a smooth implementation of accelerated failure time models.
Package details 


Author  Mark Clements [aut, cre], XingRong Liu [aut], Paul Lambert [ctb] 
Date of publication  20170920 18:30:53 UTC 
Maintainer  Mark Clements <[email protected]> 
License  GPL2  GPL3 
Version  1.4.1 
URL  http://github.com/mclements/rstpm2 
Package repository  View on CRAN 
Installation 
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