E. coli gene expression levels

Description

Gene expression levels in the bacteria Escherichia coli (E. coli), measured for 153 genes under each of 40 different experimental conditions.

Usage

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Format

Ecoli.expr is a 40 by 153 matrix of (log) gene expression levels in the bacteria Escherichia coli (E. coli), measured for 153 transcription factors under each of 40 different experimental conditions, averaged over three replicates of each experiment. The data are a subset of those published in the reference below. The experiments were genetic perturbation experiments,in which a given gene was ‘turned off’, for each of 40 different genes.

regDB.adj is an adjacency matrix of regulatory relationships in E. coli, extracted from the RegulonDB (http://regulondb.ccg.unam.mx/) database at the same time the experimental data were collected.

Source

See the reference below. Please cite it if you use this dataset in your work.

References

J. Faith, B. Hayete, J. Thaden, I. Mogno, J. Wierzbowski, G. Cottarel, S. Kasif, J. Collins, T. Gardner: Large-scale mapping and validation of Escherichia coli transcriptional regulation from a compendium of expression profiles. PLoS Biol. 5(1), e8 (2007).