Gene expression levels in the bacteria Escherichia coli (E. coli), measured for 153 genes under each of 40 different experimental conditions.
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Ecoli.expr is a 40 by 153 matrix of (log) gene expression
levels in the bacteria Escherichia coli (E. coli), measured for
153 transcription factors under each of 40 different experimental
conditions, averaged over three replicates of each experiment. The data
are a subset of those published in the reference below. The
experiments were genetic perturbation experiments,in which a given
gene was ‘turned off’, for each of 40 different genes.
regDB.adj is an adjacency matrix of regulatory relationships in
E. coli, extracted from the RegulonDB
(http://regulondb.ccg.unam.mx/) database at the same time the
experimental data were collected.
See the reference below. Please cite it if you use this dataset in your work.
J. Faith, B. Hayete, J. Thaden, I. Mogno, J. Wierzbowski, G. Cottarel, S. Kasif, J. Collins, T. Gardner: Large-scale mapping and validation of Escherichia coli transcriptional regulation from a compendium of expression profiles. PLoS Biol. 5(1), e8 (2007).