ReduceGO: Reduce scDiffCom GO Terms

In scDiffCom: Differential Analysis of Intercellular Communication from scRNA-Seq Data

Reduce scDiffCom GO Terms

Description

Perform semantic similarity analysis and reduction of the overrepresented GO terms of an scDiffCom object.

Usage

ReduceGO(
  object,
  method = c("Rel", "Resnik", "Lin", "Jiang", "Wang"),
  threshold = 0.7
)

## S4 method for signature 'scDiffCom'
ReduceGO(
  object,
  method = c("Rel", "Resnik", "Lin", "Jiang", "Wang"),
  threshold = 0.7
)

Arguments

object	scDiffCom object
method	A distance method supported by rrvgo and GOSemSim: c("Rel", "Resnik", "Lin", "Jiang", "Wang")
threshold	Similarity threshold used by rrvgo::reduceSimMatrix

Details

This function is basically a wrapper around rrvgo::calculateSimMatrix and rrvgo::reduceSimMatrix.

Value

A data.table of GO terms with their reduction

scDiffCom documentation built on Nov. 4, 2023, 1:06 a.m.