Description
Usage
Arguments
Value
Author(s)
See Also
View source: R/get.cov.matrix.R
get.cov.matrix is a secondary function called during estimation runs by
fitmle.cov. It computes the covariance matrix for the parameter
estimates. get.cov.matrix is typically not called directly by users.
problem |
A list containing the following levels:
- data
A list containing as many levels as there are treatment levels
for the subject (or population) being evaluated, plus the trts
level listing all treatments for this subject (or population), and the
id level giving the identification number of the subject (or set to
1 if the analysis was run at the level of the population.
Each treatment-specific level is a list containing the following levels:
- cov
mij x 3 data.frame containing the times of observations of the
dependent variables (extracted from the TIME variable), the indicators
of the type of dependent variables (extracted from the CMT variable),
and the actual dependent variable observations (extracted from the
DV variable) for this particular treatment.
- cov
mij x c data.frame containing the times of observations of
the dependent variables (extracted from the TIME variable) and all the
covariates identified for this particular treatment.
- bolus
bij x 4 data.frame providing the instantaneous inputs
for a treatment and individual.
- infusion
fij x (4+c) data.frame providing the zero-order inputs for
a treatment and individual.
- trt
the particular treatment identifier.
- method
A character string, indicating the scale of the analysis. Should
be 'population' or 'subject'.
- init
A data.frame of parameter data with the following columns:
'names', 'type', 'value', 'isfix', 'lb', and 'ub'.
- debugmode
Logical indicator of debugging mode.
- modfun
Model function.
|
Fit |
A list of containing the following levels:
- estimations
The vector of final parameter estimates.
- fval
The minimal value of the objective function.
|
Return a list with the following elements:
- covmatrix
The matrix of covariance for the parameter estimates.
- orderedestimations
A data.frame with the same structure as
problem$init but only containing the sorted estimated estimates.
The sorting is performed by order.param.list.
Sebastien Bihorel (sb.pmlab@gmail.com)
fitmle.cov
scaRabee documentation built on Feb. 4, 2022, 5:07 p.m.
