weighting: Residual Variability

In scaRabee: Optimization Toolkit for Pharmacokinetic-Pharmacodynamic Models

Description

weighting is a secondary function called during estimation run to evaluate the model(s) of residual variability specified by the code provided in the $VARIANCE block. weighting is typically not called directly by users.

Usage

  weighting(parms = NULL,
            derparms = NULL,
            codevar=NULL,
            y=NULL,
            xdata=NULL,
            check=FALSE)

Arguments

parms	A vector of primary parameters.
derparms	A list of derived parameters, specified in the $DERIVED block of code.
codevar	The content of the R code specified within the $VARIANCE block in the model file.
y	The matrix of structural model predictions.
xdata	A vector of times at which the system is being evaluated.
check	An indicator whether checks should be performed to validate function inputs

Value

Return a matrix of numeric values of the same dimension as f.

Author(s)

Sebastien Bihorel ([e-mail])

scaRabee documentation built on Feb. 4, 2022, 5:07 p.m.