Description Usage Arguments Details Value References See Also
Perform the similar method to sgRSEA using a simple average instead of the maxmean statistic as gene level statistics. This method is referred as T_{mean} in Noh et al. (2015+).
1 | sgRSEA.mean(dat, multiplier = 50, r.seed = NULL)
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dat |
A data.frame where rows represent sgRNAs and columns are the sgRNA name (1st), targeting gene name (2nd), and sgRNA read counts under treatment (3rd) and control (4th) condition. |
multiplier |
The number of permutations. |
r.seed |
A random seed to control the randomness of the permutation. |
Arguments and Value are the same as sgRSEA()
.
Returns the same list as sgRSEA()
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Noh, J., Chen, B., Xiao, G. and Xie, Y. (2015+). A robust test for identification of essential genes from CRISPR/Cas9 knockout screens.
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