deepvein: Deep Vein Thrombosis Study

In shrink: Global, Parameterwise and Joint Shrinkage Factor Estimation

Deep Vein Thrombosis Study

Description

A data frame containing time to recurrence of thrombosis and several potential prognostic factors measured at baseline for 929 individuals with deep vein thrombosis or unprovoked pulmonary embolism. 147 events of recurrence were observed during a median follow-up time of 37.8 months.

Usage

deepvein

Format

The data frame contains observations of 929 individuals and the following variables:

pnr

patient number.

time

time to recurrence of thrombosis or end of study in months.

status

= 1 recurrence of thrombosis.

sex

gender.

fiimut

factor II G20210A mutation.

fvleid

factor V Leiden mutation.

log2ddim

log2-transformed D-dimer.

bmi

body mass index.

durther

duration of anticoagulation therapy.

age

age in years.

loc

location of first thrombosis: pulmonary embolism (PE), distal, or proximal deep vein
thrombosis.

Note

The data are a modified and partly simulated version of the data set used by Eichinger et al. (2010) and are available under a GPL-2 license.

References

M. Schumacher, G. Basert, H. Bojar, K. Huebner, M. Olschewski, W. Sauerbrei, C. Schmoor, C. Beyerle, R.L.A. Neumann and H.F. Rauschecker for the German Breast Cancer Study Group (1994). Randomized 2 \times 2 trial evaluating hormonal treatment and the duration of chemotherapy in node-positive breast cancer patients. Journal of Clinical Oncology, 12, 2086–2093.
W. Sauerbrei and P. Royston (1999). Building multivariable prognostic and diagnostic models: transformation of the predictors by using fractional polynomials. Journal of the Royal Statistics Society Series A, Volume 162(1), 71–94.

Examples

 data("deepvein")
 summary(deepvein)

shrink documentation built on Nov. 2, 2023, 6:05 p.m.