Imports Variant Calling Format file into R. It can detect whether a sample contains contaminant from the same species. In the first stage of the approach, a change-point detection method is used to identify copy number variations for filtering. Next, features are extracted from the data for a support vector machine model. For log-likelihood calculation, the deviation parameter is estimated by maximum likelihood method. Using a radial basis function kernel support vector machine, the contamination of a sample can be detected.
|Author||Tao Jiang [aut, cre]|
|Date of publication||2018-06-15 11:22:54 UTC|
|Maintainer||Tao Jiang <[email protected]>|
|Package repository||View on CRAN|
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