sumFREGAT: Fast Region-Based Association Tests on Summary Statistics

An adaptation of classical region/gene-based association analysis techniques to the use of summary statistics (P values and effect sizes) and correlations between genetic variants as input. It is a tool to perform the most popular and efficient gene-based tests using the results of genome-wide association (meta-)analyses without having the original genotypes and phenotypes at hand.

Package details

AuthorNadezhda M. Belonogova <> and Gulnara R. Svishcheva <> with contributions from: Seunggeun Lee (kernel functions), Pierre Lafaye de Micheaux ('davies' method), Minghui Wang, Yiyuan Liu, Shizhong Han (simpleM function) Thomas Lumley ('kuonen' method), and James O. Ramsay (functional data analysis functions)
MaintainerNadezhda M. Belonogova <>
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:

Try the sumFREGAT package in your browser

Any scripts or data that you put into this service are public.

sumFREGAT documentation built on May 2, 2019, 5:52 a.m.