The sumFREGAT package computes the most popular and efficient tests for the region-based association analysis using summary statistics data (beta and P values) and correlations between genetic variants. It does not require genotype or phenotype data. Methods implemented are SKAT and SKAT-O (sequence kernel association tests), BT (burden test), FLM (functional linear model), PCA (principal components analysis), MLR (multiple linear regression), and others.
Nadezhda Belonogova <firstname.lastname@example.org>
Gulnara Svishcheva <email@example.com>
The authors are grateful to Dr. Anatoly Kirichenko for technical support
and Prof. Tatiana Axenovich for scientific guidance.
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