estimate_incidence_rate.md
In tern: Create Common TLGs Used in Clinical Trials

control_incidence_rate works with customized parameters

Code
  res
Output
  $conf_level
  [1] 0.9

  $conf_type
  [1] "exact"

  $input_time_unit
  [1] "month"

  $num_pt_year
  [1] 100

h_incidence_rate_normal works as expected with healthy input

Code
  res
Output
  $rate
  [1] 0.01

  $rate_ci
  [1] -0.001630872  0.021630872

h_incidence_rate_normal_log works as expected with healthy input

Code
  res
Output
  $rate
  [1] 0.01

  $rate_ci
  [1] 0.003125199 0.031997963

h_incidence_rate_exact works as expected with healthy input

Code
  res
Output
  $rate
  [1] 0.01

  $rate_ci
  [1] 0.001776808 0.031478968

h_incidence_rate_byar works as expected with healthy input

Code
  res
Output
  $rate
  [1] 0.01

  $rate_ci
  [1] 0.002820411 0.027609866

h_incidence_rate works as expected with healthy input

Code
  res
Output
  $rate
  [1] 1

  $rate_ci
  [1] 0.3125199 3.1997963

s_incidence_rate works as expected with healthy input

Code
  res
Output
  $person_years
  [1] 9.058333
  attr(,"label")
  [1] "Total patient-years at risk"

  $n_events
  [1] 4
  attr(,"label")
  [1] "Number of adverse events observed"

  $rate
  [1] 44.15823
  attr(,"label")
  [1] "AE rate per 100 patient-years"

  $rate_ci
  [1]  19.40154 100.50487
  attr(,"label")
  [1] "90% CI"

estimate_incidence_rate works as expected with healthy input

Code
  res
Output
                                            A                 B       
                                          (N=3)             (N=3)     
  ————————————————————————————————————————————————————————————————————
  Total patient-years at risk              3.8               5.2      
  Number of adverse events observed         1                 3       
  AE rate per 100 patient-years           26.20             57.23     
  90% CI                              (5.06, 135.73)   (22.14, 147.94)