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Create Common TLGs Used in Clinical Trials

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tests/testthat/_snaps/h_adsl_adlb_merge_using_worst_flag.md

tests/testthat/_snaps/h_adsl_adlb_merge_using_worst_flag.md
In tern: Create Common TLGs Used in Clinical Trials

h_adsl_adlb_merge_using_worst_flag generates missing for patients without any lab

Code
  res
Output
                  USUBJID PARAMCD                                PARAM
  1  AB12345-CHN-3-id-128     ALT Alanine Aminotransferase Measurement
  2  AB12345-CHN-3-id-128     CRP       C-Reactive Protein Measurement
  3  AB12345-CHN-3-id-128     IGA         Immunoglobulin A Measurement
  4 AB12345-CHN-11-id-175     ALT Alanine Aminotransferase Measurement
  5 AB12345-CHN-11-id-175     CRP       C-Reactive Protein Measurement
  6 AB12345-CHN-11-id-175     IGA         Immunoglobulin A Measurement
           AVISIT AVISITN    ATOXGR    BTOXGR STUDYID COUNTRY SITEID SUBJID
  1 WEEK 4 DAY 29       4         1         0 AB12345     CHN  CHN-3 id-128
  2 WEEK 5 DAY 36       5         3         0 AB12345     CHN  CHN-3 id-128
  3 WEEK 5 DAY 36       5         4         0 AB12345     CHN  CHN-3 id-128
  4     <Missing>      NA <Missing> <Missing> AB12345     CHN CHN-11 id-175
  5     <Missing>      NA <Missing> <Missing> AB12345     CHN CHN-11 id-175
  6     <Missing>      NA <Missing> <Missing> AB12345     CHN CHN-11 id-175
         AGE SEX ARMCD        ARM ACTARMCD     ACTARM  RACE             TRTSDTM
  1 36.12988   M ARM B B: Placebo    ARM B B: Placebo ASIAN 2021-01-01 09:05:27
  2 36.12988   M ARM B B: Placebo    ARM B B: Placebo ASIAN 2021-01-01 09:05:27
  3 36.12988   M ARM B B: Placebo    ARM B B: Placebo ASIAN 2021-01-01 09:05:27
  4 38.29802   F ARM B B: Placebo    ARM B B: Placebo ASIAN 2019-11-03 18:20:42
  5 38.29802   F ARM B B: Placebo    ARM B B: Placebo ASIAN 2019-11-03 18:20:42
  6 38.29802   F ARM B B: Placebo    ARM B B: Placebo ASIAN 2019-11-03 18:20:42
                TRTEDTM EOSDY STRATA1 STRATA2    BMRKR1 BMRKR2 REGION1 SAFFL
  1 2023-01-01 21:05:27   731       C      S1  7.677225 MEDIUM    Asia     Y
  2 2023-01-01 21:05:27   731       C      S1  7.677225 MEDIUM    Asia     Y
  3 2023-01-01 21:05:27   731       C      S1  7.677225 MEDIUM    Asia     Y
  4 2021-11-03 06:20:42   731       B      S1 11.351954    LOW    Asia     Y
  5 2021-11-03 06:20:42   731       B      S1 11.351954    LOW    Asia     Y
  6 2021-11-03 06:20:42   731       B      S1 11.351954    LOW    Asia     Y

h_adsl_adlb_merge_using_worst_flag generates missing for patients missing baseline lab

Code
  res
Output
                  USUBJID PARAMCD                                PARAM
  1 AB12345-CHN-11-id-175     ALT Alanine Aminotransferase Measurement
  2 AB12345-CHN-11-id-175     CRP       C-Reactive Protein Measurement
  3 AB12345-CHN-11-id-175     IGA         Immunoglobulin A Measurement
  4  AB12345-CHN-3-id-128     ALT Alanine Aminotransferase Measurement
  5  AB12345-CHN-3-id-128     CRP       C-Reactive Protein Measurement
  6  AB12345-CHN-3-id-128     IGA         Immunoglobulin A Measurement
           AVISIT AVISITN ATOXGR    BTOXGR STUDYID COUNTRY SITEID SUBJID      AGE
  1  WEEK 1 DAY 8       1      0 <Missing> AB12345     CHN CHN-11 id-175 38.29802
  2 WEEK 2 DAY 15       2      0 <Missing> AB12345     CHN CHN-11 id-175 38.29802
  3  WEEK 1 DAY 8       1      2 <Missing> AB12345     CHN CHN-11 id-175 38.29802
  4 WEEK 4 DAY 29       4      1         0 AB12345     CHN  CHN-3 id-128 36.12988
  5 WEEK 5 DAY 36       5      3         0 AB12345     CHN  CHN-3 id-128 36.12988
  6 WEEK 5 DAY 36       5      4         0 AB12345     CHN  CHN-3 id-128 36.12988
    SEX ARMCD        ARM ACTARMCD     ACTARM  RACE             TRTSDTM
  1   F ARM B B: Placebo    ARM B B: Placebo ASIAN 2019-11-03 18:20:42
  2   F ARM B B: Placebo    ARM B B: Placebo ASIAN 2019-11-03 18:20:42
  3   F ARM B B: Placebo    ARM B B: Placebo ASIAN 2019-11-03 18:20:42
  4   M ARM B B: Placebo    ARM B B: Placebo ASIAN 2021-01-01 09:05:27
  5   M ARM B B: Placebo    ARM B B: Placebo ASIAN 2021-01-01 09:05:27
  6   M ARM B B: Placebo    ARM B B: Placebo ASIAN 2021-01-01 09:05:27
                TRTEDTM EOSDY STRATA1 STRATA2    BMRKR1 BMRKR2 REGION1 SAFFL
  1 2021-11-03 06:20:42   731       B      S1 11.351954    LOW    Asia     Y
  2 2021-11-03 06:20:42   731       B      S1 11.351954    LOW    Asia     Y
  3 2021-11-03 06:20:42   731       B      S1 11.351954    LOW    Asia     Y
  4 2023-01-01 21:05:27   731       C      S1  7.677225 MEDIUM    Asia     Y
  5 2023-01-01 21:05:27   731       C      S1  7.677225 MEDIUM    Asia     Y
  6 2023-01-01 21:05:27   731       C      S1  7.677225 MEDIUM    Asia     Y

h_adsl_adlb_merge_using_worst_flag generates missing for patients missing post-baseline lab

Code
  res
Output
                  USUBJID PARAMCD                                PARAM
  1 AB12345-CHN-11-id-175     ALT Alanine Aminotransferase Measurement
  2 AB12345-CHN-11-id-175     CRP       C-Reactive Protein Measurement
  3 AB12345-CHN-11-id-175     IGA         Immunoglobulin A Measurement
  4  AB12345-CHN-3-id-128     ALT Alanine Aminotransferase Measurement
  5  AB12345-CHN-3-id-128     CRP       C-Reactive Protein Measurement
  6  AB12345-CHN-3-id-128     IGA         Immunoglobulin A Measurement
           AVISIT AVISITN    ATOXGR BTOXGR STUDYID COUNTRY SITEID SUBJID      AGE
  1  WEEK 1 DAY 8       1 <Missing>      0 AB12345     CHN CHN-11 id-175 38.29802
  2 WEEK 2 DAY 15       2 <Missing>      0 AB12345     CHN CHN-11 id-175 38.29802
  3  WEEK 1 DAY 8       1 <Missing>      1 AB12345     CHN CHN-11 id-175 38.29802
  4 WEEK 4 DAY 29       4         1      0 AB12345     CHN  CHN-3 id-128 36.12988
  5 WEEK 5 DAY 36       5         3      0 AB12345     CHN  CHN-3 id-128 36.12988
  6 WEEK 5 DAY 36       5         4      0 AB12345     CHN  CHN-3 id-128 36.12988
    SEX ARMCD        ARM ACTARMCD     ACTARM  RACE             TRTSDTM
  1   F ARM B B: Placebo    ARM B B: Placebo ASIAN 2019-11-03 18:20:42
  2   F ARM B B: Placebo    ARM B B: Placebo ASIAN 2019-11-03 18:20:42
  3   F ARM B B: Placebo    ARM B B: Placebo ASIAN 2019-11-03 18:20:42
  4   M ARM B B: Placebo    ARM B B: Placebo ASIAN 2021-01-01 09:05:27
  5   M ARM B B: Placebo    ARM B B: Placebo ASIAN 2021-01-01 09:05:27
  6   M ARM B B: Placebo    ARM B B: Placebo ASIAN 2021-01-01 09:05:27
                TRTEDTM EOSDY STRATA1 STRATA2    BMRKR1 BMRKR2 REGION1 SAFFL
  1 2021-11-03 06:20:42   731       B      S1 11.351954    LOW    Asia     Y
  2 2021-11-03 06:20:42   731       B      S1 11.351954    LOW    Asia     Y
  3 2021-11-03 06:20:42   731       B      S1 11.351954    LOW    Asia     Y
  4 2023-01-01 21:05:27   731       C      S1  7.677225 MEDIUM    Asia     Y
  5 2023-01-01 21:05:27   731       C      S1  7.677225 MEDIUM    Asia     Y
  6 2023-01-01 21:05:27   731       C      S1  7.677225 MEDIUM    Asia     Y

h_adsl_adlb_merge_using_worst_flag generates missing for patients without any worst flagged post-baseline values

Code
  res
Output
                  USUBJID PARAMCD                                PARAM
  1  AB12345-CHN-3-id-128     ALT Alanine Aminotransferase Measurement
  2  AB12345-CHN-3-id-128     CRP       C-Reactive Protein Measurement
  3  AB12345-CHN-3-id-128     IGA         Immunoglobulin A Measurement
  4 AB12345-CHN-11-id-175     ALT Alanine Aminotransferase Measurement
  5 AB12345-CHN-11-id-175     CRP       C-Reactive Protein Measurement
  6 AB12345-CHN-11-id-175     IGA         Immunoglobulin A Measurement
           AVISIT AVISITN    ATOXGR    BTOXGR STUDYID COUNTRY SITEID SUBJID
  1 WEEK 4 DAY 29       4         1         0 AB12345     CHN  CHN-3 id-128
  2 WEEK 5 DAY 36       5         3         0 AB12345     CHN  CHN-3 id-128
  3 WEEK 5 DAY 36       5         4         0 AB12345     CHN  CHN-3 id-128
  4     <Missing>      NA <Missing> <Missing> AB12345     CHN CHN-11 id-175
  5     <Missing>      NA <Missing> <Missing> AB12345     CHN CHN-11 id-175
  6     <Missing>      NA <Missing> <Missing> AB12345     CHN CHN-11 id-175
         AGE SEX ARMCD        ARM ACTARMCD     ACTARM  RACE             TRTSDTM
  1 36.12988   M ARM B B: Placebo    ARM B B: Placebo ASIAN 2021-01-01 09:05:27
  2 36.12988   M ARM B B: Placebo    ARM B B: Placebo ASIAN 2021-01-01 09:05:27
  3 36.12988   M ARM B B: Placebo    ARM B B: Placebo ASIAN 2021-01-01 09:05:27
  4 38.29802   F ARM B B: Placebo    ARM B B: Placebo ASIAN 2019-11-03 18:20:42
  5 38.29802   F ARM B B: Placebo    ARM B B: Placebo ASIAN 2019-11-03 18:20:42
  6 38.29802   F ARM B B: Placebo    ARM B B: Placebo ASIAN 2019-11-03 18:20:42
                TRTEDTM EOSDY STRATA1 STRATA2    BMRKR1 BMRKR2 REGION1 SAFFL
  1 2023-01-01 21:05:27   731       C      S1  7.677225 MEDIUM    Asia     Y
  2 2023-01-01 21:05:27   731       C      S1  7.677225 MEDIUM    Asia     Y
  3 2023-01-01 21:05:27   731       C      S1  7.677225 MEDIUM    Asia     Y
  4 2021-11-03 06:20:42   731       B      S1 11.351954    LOW    Asia     Y
  5 2021-11-03 06:20:42   731       B      S1 11.351954    LOW    Asia     Y
  6 2021-11-03 06:20:42   731       B      S1 11.351954    LOW    Asia     Y

h_adsl_adlb_merge_using_worst_flag generates missing and by visit lab results

Code
  res
Output
                   USUBJID        AVISIT AVISITN PARAMCD
  1   AB12345-CHN-3-id-128  WEEK 1 DAY 8       1     ALT
  2   AB12345-CHN-3-id-128 WEEK 2 DAY 15       2     ALT
  3   AB12345-CHN-3-id-128 WEEK 3 DAY 22       3     ALT
  4   AB12345-CHN-3-id-128 WEEK 4 DAY 29       4     ALT
  5   AB12345-CHN-3-id-128 WEEK 5 DAY 36       5     ALT
  6   AB12345-CHN-3-id-128  WEEK 1 DAY 8       1     CRP
  7   AB12345-CHN-3-id-128 WEEK 2 DAY 15       2     CRP
  8   AB12345-CHN-3-id-128 WEEK 3 DAY 22       3     CRP
  9   AB12345-CHN-3-id-128 WEEK 4 DAY 29       4     CRP
  10  AB12345-CHN-3-id-128 WEEK 5 DAY 36       5     CRP
  11  AB12345-CHN-3-id-128  WEEK 1 DAY 8       1     IGA
  12  AB12345-CHN-3-id-128 WEEK 2 DAY 15       2     IGA
  13  AB12345-CHN-3-id-128 WEEK 3 DAY 22       3     IGA
  14  AB12345-CHN-3-id-128 WEEK 4 DAY 29       4     IGA
  15  AB12345-CHN-3-id-128 WEEK 5 DAY 36       5     IGA
  16 AB12345-CHN-11-id-175  WEEK 1 DAY 8       1     ALT
  17 AB12345-CHN-11-id-175 WEEK 2 DAY 15       2     ALT
  18 AB12345-CHN-11-id-175 WEEK 3 DAY 22       3     ALT
  19 AB12345-CHN-11-id-175 WEEK 4 DAY 29       4     ALT
  20 AB12345-CHN-11-id-175 WEEK 5 DAY 36       5     ALT
  21 AB12345-CHN-11-id-175  WEEK 1 DAY 8       1     CRP
  22 AB12345-CHN-11-id-175 WEEK 2 DAY 15       2     CRP
  23 AB12345-CHN-11-id-175 WEEK 3 DAY 22       3     CRP
  24 AB12345-CHN-11-id-175 WEEK 4 DAY 29       4     CRP
  25 AB12345-CHN-11-id-175 WEEK 5 DAY 36       5     CRP
  26 AB12345-CHN-11-id-175  WEEK 1 DAY 8       1     IGA
  27 AB12345-CHN-11-id-175 WEEK 2 DAY 15       2     IGA
  28 AB12345-CHN-11-id-175 WEEK 3 DAY 22       3     IGA
  29 AB12345-CHN-11-id-175 WEEK 4 DAY 29       4     IGA
  30 AB12345-CHN-11-id-175 WEEK 5 DAY 36       5     IGA
                                    PARAM    ATOXGR    BTOXGR STUDYID COUNTRY
  1  Alanine Aminotransferase Measurement         0         0 AB12345     CHN
  2  Alanine Aminotransferase Measurement         0         0 AB12345     CHN
  3  Alanine Aminotransferase Measurement         0         0 AB12345     CHN
  4  Alanine Aminotransferase Measurement         1         0 AB12345     CHN
  5  Alanine Aminotransferase Measurement        -4         0 AB12345     CHN
  6        C-Reactive Protein Measurement         0         0 AB12345     CHN
  7        C-Reactive Protein Measurement         0         0 AB12345     CHN
  8        C-Reactive Protein Measurement         0         0 AB12345     CHN
  9        C-Reactive Protein Measurement         2         0 AB12345     CHN
  10       C-Reactive Protein Measurement         3         0 AB12345     CHN
  11         Immunoglobulin A Measurement        -1         0 AB12345     CHN
  12         Immunoglobulin A Measurement         0         0 AB12345     CHN
  13         Immunoglobulin A Measurement         0         0 AB12345     CHN
  14         Immunoglobulin A Measurement        -4         0 AB12345     CHN
  15         Immunoglobulin A Measurement         4         0 AB12345     CHN
  16 Alanine Aminotransferase Measurement <Missing> <Missing> AB12345     CHN
  17 Alanine Aminotransferase Measurement <Missing> <Missing> AB12345     CHN
  18 Alanine Aminotransferase Measurement <Missing> <Missing> AB12345     CHN
  19 Alanine Aminotransferase Measurement <Missing> <Missing> AB12345     CHN
  20 Alanine Aminotransferase Measurement <Missing> <Missing> AB12345     CHN
  21       C-Reactive Protein Measurement <Missing> <Missing> AB12345     CHN
  22       C-Reactive Protein Measurement <Missing> <Missing> AB12345     CHN
  23       C-Reactive Protein Measurement <Missing> <Missing> AB12345     CHN
  24       C-Reactive Protein Measurement <Missing> <Missing> AB12345     CHN
  25       C-Reactive Protein Measurement <Missing> <Missing> AB12345     CHN
  26         Immunoglobulin A Measurement <Missing> <Missing> AB12345     CHN
  27         Immunoglobulin A Measurement <Missing> <Missing> AB12345     CHN
  28         Immunoglobulin A Measurement <Missing> <Missing> AB12345     CHN
  29         Immunoglobulin A Measurement <Missing> <Missing> AB12345     CHN
  30         Immunoglobulin A Measurement <Missing> <Missing> AB12345     CHN
     SITEID SUBJID      AGE SEX ARMCD        ARM ACTARMCD     ACTARM  RACE
  1   CHN-3 id-128 36.12988   M ARM B B: Placebo    ARM B B: Placebo ASIAN
  2   CHN-3 id-128 36.12988   M ARM B B: Placebo    ARM B B: Placebo ASIAN
  3   CHN-3 id-128 36.12988   M ARM B B: Placebo    ARM B B: Placebo ASIAN
  4   CHN-3 id-128 36.12988   M ARM B B: Placebo    ARM B B: Placebo ASIAN
  5   CHN-3 id-128 36.12988   M ARM B B: Placebo    ARM B B: Placebo ASIAN
  6   CHN-3 id-128 36.12988   M ARM B B: Placebo    ARM B B: Placebo ASIAN
  7   CHN-3 id-128 36.12988   M ARM B B: Placebo    ARM B B: Placebo ASIAN
  8   CHN-3 id-128 36.12988   M ARM B B: Placebo    ARM B B: Placebo ASIAN
  9   CHN-3 id-128 36.12988   M ARM B B: Placebo    ARM B B: Placebo ASIAN
  10  CHN-3 id-128 36.12988   M ARM B B: Placebo    ARM B B: Placebo ASIAN
  11  CHN-3 id-128 36.12988   M ARM B B: Placebo    ARM B B: Placebo ASIAN
  12  CHN-3 id-128 36.12988   M ARM B B: Placebo    ARM B B: Placebo ASIAN
  13  CHN-3 id-128 36.12988   M ARM B B: Placebo    ARM B B: Placebo ASIAN
  14  CHN-3 id-128 36.12988   M ARM B B: Placebo    ARM B B: Placebo ASIAN
  15  CHN-3 id-128 36.12988   M ARM B B: Placebo    ARM B B: Placebo ASIAN
  16 CHN-11 id-175 38.29802   F ARM B B: Placebo    ARM B B: Placebo ASIAN
  17 CHN-11 id-175 38.29802   F ARM B B: Placebo    ARM B B: Placebo ASIAN
  18 CHN-11 id-175 38.29802   F ARM B B: Placebo    ARM B B: Placebo ASIAN
  19 CHN-11 id-175 38.29802   F ARM B B: Placebo    ARM B B: Placebo ASIAN
  20 CHN-11 id-175 38.29802   F ARM B B: Placebo    ARM B B: Placebo ASIAN
  21 CHN-11 id-175 38.29802   F ARM B B: Placebo    ARM B B: Placebo ASIAN
  22 CHN-11 id-175 38.29802   F ARM B B: Placebo    ARM B B: Placebo ASIAN
  23 CHN-11 id-175 38.29802   F ARM B B: Placebo    ARM B B: Placebo ASIAN
  24 CHN-11 id-175 38.29802   F ARM B B: Placebo    ARM B B: Placebo ASIAN
  25 CHN-11 id-175 38.29802   F ARM B B: Placebo    ARM B B: Placebo ASIAN
  26 CHN-11 id-175 38.29802   F ARM B B: Placebo    ARM B B: Placebo ASIAN
  27 CHN-11 id-175 38.29802   F ARM B B: Placebo    ARM B B: Placebo ASIAN
  28 CHN-11 id-175 38.29802   F ARM B B: Placebo    ARM B B: Placebo ASIAN
  29 CHN-11 id-175 38.29802   F ARM B B: Placebo    ARM B B: Placebo ASIAN
  30 CHN-11 id-175 38.29802   F ARM B B: Placebo    ARM B B: Placebo ASIAN
                 TRTSDTM             TRTEDTM EOSDY STRATA1 STRATA2    BMRKR1
  1  2021-01-01 09:05:27 2023-01-01 21:05:27   731       C      S1  7.677225
  2  2021-01-01 09:05:27 2023-01-01 21:05:27   731       C      S1  7.677225
  3  2021-01-01 09:05:27 2023-01-01 21:05:27   731       C      S1  7.677225
  4  2021-01-01 09:05:27 2023-01-01 21:05:27   731       C      S1  7.677225
  5  2021-01-01 09:05:27 2023-01-01 21:05:27   731       C      S1  7.677225
  6  2021-01-01 09:05:27 2023-01-01 21:05:27   731       C      S1  7.677225
  7  2021-01-01 09:05:27 2023-01-01 21:05:27   731       C      S1  7.677225
  8  2021-01-01 09:05:27 2023-01-01 21:05:27   731       C      S1  7.677225
  9  2021-01-01 09:05:27 2023-01-01 21:05:27   731       C      S1  7.677225
  10 2021-01-01 09:05:27 2023-01-01 21:05:27   731       C      S1  7.677225
  11 2021-01-01 09:05:27 2023-01-01 21:05:27   731       C      S1  7.677225
  12 2021-01-01 09:05:27 2023-01-01 21:05:27   731       C      S1  7.677225
  13 2021-01-01 09:05:27 2023-01-01 21:05:27   731       C      S1  7.677225
  14 2021-01-01 09:05:27 2023-01-01 21:05:27   731       C      S1  7.677225
  15 2021-01-01 09:05:27 2023-01-01 21:05:27   731       C      S1  7.677225
  16 2019-11-03 18:20:42 2021-11-03 06:20:42   731       B      S1 11.351954
  17 2019-11-03 18:20:42 2021-11-03 06:20:42   731       B      S1 11.351954
  18 2019-11-03 18:20:42 2021-11-03 06:20:42   731       B      S1 11.351954
  19 2019-11-03 18:20:42 2021-11-03 06:20:42   731       B      S1 11.351954
  20 2019-11-03 18:20:42 2021-11-03 06:20:42   731       B      S1 11.351954
  21 2019-11-03 18:20:42 2021-11-03 06:20:42   731       B      S1 11.351954
  22 2019-11-03 18:20:42 2021-11-03 06:20:42   731       B      S1 11.351954
  23 2019-11-03 18:20:42 2021-11-03 06:20:42   731       B      S1 11.351954
  24 2019-11-03 18:20:42 2021-11-03 06:20:42   731       B      S1 11.351954
  25 2019-11-03 18:20:42 2021-11-03 06:20:42   731       B      S1 11.351954
  26 2019-11-03 18:20:42 2021-11-03 06:20:42   731       B      S1 11.351954
  27 2019-11-03 18:20:42 2021-11-03 06:20:42   731       B      S1 11.351954
  28 2019-11-03 18:20:42 2021-11-03 06:20:42   731       B      S1 11.351954
  29 2019-11-03 18:20:42 2021-11-03 06:20:42   731       B      S1 11.351954
  30 2019-11-03 18:20:42 2021-11-03 06:20:42   731       B      S1 11.351954
     BMRKR2 REGION1 SAFFL
  1  MEDIUM    Asia     Y
  2  MEDIUM    Asia     Y
  3  MEDIUM    Asia     Y
  4  MEDIUM    Asia     Y
  5  MEDIUM    Asia     Y
  6  MEDIUM    Asia     Y
  7  MEDIUM    Asia     Y
  8  MEDIUM    Asia     Y
  9  MEDIUM    Asia     Y
  10 MEDIUM    Asia     Y
  11 MEDIUM    Asia     Y
  12 MEDIUM    Asia     Y
  13 MEDIUM    Asia     Y
  14 MEDIUM    Asia     Y
  15 MEDIUM    Asia     Y
  16    LOW    Asia     Y
  17    LOW    Asia     Y
  18    LOW    Asia     Y
  19    LOW    Asia     Y
  20    LOW    Asia     Y
  21    LOW    Asia     Y
  22    LOW    Asia     Y
  23    LOW    Asia     Y
  24    LOW    Asia     Y
  25    LOW    Asia     Y
  26    LOW    Asia     Y
  27    LOW    Asia     Y
  28    LOW    Asia     Y
  29    LOW    Asia     Y
  30    LOW    Asia     Y


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