Description Usage Arguments Value Author(s) References
Sort all genes in the dataset by their Kullback Leibler distance ratios or p-values.
1 | timeSeq.sort(genenames,npde,pde,table,count,pvalue)
|
genenames |
a vector of gene names. |
npde |
a vector of Kullback Leibler distance ratios or p-values for NPDE genes. |
pde |
a vector of Kullback Leibler distance ratios or p-values for PDE genes. |
table |
gene expression values. |
count |
the number of exons or replicates for each gene. |
pvalue |
logical:indicating if p-values are returned. |
A list with components
npde.list |
dataframe of NPDE genes sorted by KLRs or p-values. |
pde.list |
dataframe of PDE genes sorted by KLRs or p-values. |
table1 |
gene expression values for each gene, corresponding to npde.list. |
table2 |
gene expression values for each gene, corresponding to pde.list. |
Fan Gao and Xiaoxiao Sun
Sun, Xiaoxiao, David Dalpiaz, Di Wu, Jun S. Liu, Wenxuan Zhong, and Ping Ma. "Statistical inference for time course RNA-Seq data using a negative binomial mixed-effect model." BMC Bioinformatics, 17(1):324, 2016.
Chong Gu. Model diagnostics for smoothing spline ANOVA models. Canadian Journal of Statistics, 32(4):347-358, 2004.
Chong Gu. Smoothing spline ANOVA models. Springer, second edition, 2013.
Chong Gu and Ping Ma. Optimal smoothing in nonparametric mixed-effect models. Annals of Statistics, pages 1357-1379, 2005a.
Wood (2001) mgcv:GAMs and Generalized Ridge Regression for R. R News 1(2):20-25
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