tip_hr_with_binary: Tip an observed hazard ratio with a binary confounder.

In tipr: Tipping Point Analyses

Tip an observed hazard ratio with a binary confounder.

Description

Choose two of the following three to specify, and the third will be estimated:

• exposed_confounder_prev

• unexposed_confounder_prev

• confounder_outcome_effect

Alternatively, specify all three and the function will return the number of unmeasured confounders specified needed to tip the analysis.

Usage

tip_hr_with_binary(
  effect_observed,
  exposed_confounder_prev = NULL,
  unexposed_confounder_prev = NULL,
  confounder_outcome_effect = NULL,
  verbose = TRUE,
  hr_correction = FALSE
)

Arguments

effect_observed	Numeric positive value. Observed exposure - outcome hazard ratio. This can be the point estimate, lower confidence bound, or upper confidence bound.
exposed_confounder_prev	Numeric between 0 and 1. Estimated prevalence of the unmeasured confounder in the exposed population
unexposed_confounder_prev	Numeric between 0 and 1. Estimated prevalence of the unmeasured confounder in the unexposed population
confounder_outcome_effect	Numeric positive value. Estimated relationship between the unmeasured confounder and the outcome
verbose	Logical. Indicates whether to print informative message. Default: TRUE
hr_correction	Logical. Indicates whether to use a correction factor. The methods used for this function are based on risk ratios. For rare outcomes, a hazard ratio approximates a risk ratio. For common outcomes, a correction factor is needed. If you have a common outcome (>15%), set this to TRUE. Default: FALSE.

Value

Data frame.

Examples

tip_hr_with_binary(0.9, 0.9, 0.1)

tipr documentation built on Sept. 5, 2022, 5:09 p.m.