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Functions to design phase 1 trials using an isotonic regression based design incorporating time-to-event information. Simulation and design functions are available, which incorporate information about followup and DLTs, and apply isotonic regression to devise estimates of DLT probability.
Package details |
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Author | Lee McDaniel [aut, cre] |
Maintainer | Lee McDaniel <lmcda4@lsuhsc.edu> |
License | GPL-3 |
Version | 0.1.0 |
Package repository | View on CRAN |
Installation |
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