titeIR: Isotonic Designs for Phase 1 Trials with Late-Onset Toxicities

Functions to design phase 1 trials using an isotonic regression based design incorporating time-to-event information. Simulation and design functions are available, which incorporate information about followup and DLTs, and apply isotonic regression to devise estimates of DLT probability.

Getting started

Package details

AuthorLee McDaniel [aut, cre]
MaintainerLee McDaniel <[email protected]>
LicenseGPL-3
Version0.1.0
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("titeIR")

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titeIR documentation built on Sept. 29, 2018, 1:03 a.m.