Functions to design phase 1 trials using an isotonic regression based design incorporating time-to-event information. Simulation and design functions are available, which incorporate information about followup and DLTs, and apply isotonic regression to devise estimates of DLT probability.
|Author||Lee McDaniel [aut, cre]|
|Maintainer||Lee McDaniel <[email protected]>|
|Package repository||View on CRAN|
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