Calculates negative log likelihood for beta binomial distribution.
1 | negll(x, size, prob, rho)
|
x |
Depth of alternative allele |
size |
Total depth |
prob |
Theoretical probability for heterozygous is 0.5, for homozygous is 0.999 |
rho |
Rho parameter of Beta-Binomial distribution of alternative allele |
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