cytokine: Cytokine signaling genes SNP annotation.

In varbvs: Large-Scale Bayesian Variable Selection Using Variational Methods

Cytokine signaling genes SNP annotation.

Description

This gene set was selected in Carbonetto and Stephens (2013) from an interrogation of 3,158 derived from 8 publicly available pathway databases.

Usage

data(cytokine)

Format

cytokine[i] = 1 if SNP i lies within 100 kb of a gene in the "Cytokine signaling in immune system" gene set, and cytokine[i] = 0 otherwise.

Source

Pathway id 75790 from the Reactome database, or pathway id 366171 from the BioSystems database.

References

P. Carbonetto and M. Stephens (2013). Integrated enrichment analysis of variants and pathways in genome-wide association studies indicates central role for IL-2 signaling genes in type 1 diabetes, and cytokine signaling genes in Crohn's disease. PLoS Genetics 9, e1003770.

Examples

  # See demo.cytokine.R vignette.

varbvs documentation built on June 7, 2023, 5:43 p.m.