update-Effloglog-method: Update method for the 'Effloglog' Model class. This is a...

In 0liver0815/onc-crmpack-test: Object-Oriented Implementation of CRM Designs

Description

Update method for the 'Effloglog' Model class. This is a method to update the modal estimates of the model parameters θ_1 (theta1), θ_2 (theta2) and ν (nu, the precision of the efficacy responses) when new data or new observations of responses are available and added in.

Usage

## S4 method for signature 'Effloglog'
update(object, data, ...)

Arguments

object	the Effloglog class object
data	all currently available data or responses of DataDual class object
...	unused

Value

the new Effloglog class object

Examples

##Update the 'Effloglog' model with new data
## first define the data and the model
emptydata<-DataDual(doseGrid=seq(25,300,25),placebo=FALSE)
data<-emptydata

Effmodel<-Effloglog(Eff=c(1.223,2.513),Effdose=c(25,300),nu=c(a=1,b=0.025),data=data,c=0)

##Then we have some new observations data
data<-DataDual(x=c(25,50,50,75,100,100,225,300),y=c(0,0,0,0,1,1,1,1),
               w=c(0.31,0.42,0.59,0.45,0.6,0.7,0.6,0.52),
               doseGrid=seq(25,300,25))

##update the model to get new estimates
newEffModel <- update(object=Effmodel,data=data)

0liver0815/onc-crmpack-test documentation built on Feb. 19, 2022, 12:25 a.m.