examples/mcmc-EffFlexi.R

In 0liver0815/onc-crmpack-test: Object-Oriented Implementation of CRM Designs

##obtain mcmc efficacy samples given the data, 'EffFlexi' model (efficacy model) and 
## mcmc simulations options
## data must be of 'DataDual' class
data<-DataDual(x=c(25,50,25,50,75,300,250,150),
               y=c(0,0,0,0,0,1,1,0),
               w=c(0.31,0.42,0.59,0.45,0.6,0.7,0.6,0.52),
               doseGrid=seq(25,300,25))
## model must be of 'EffFlexi' class

Effmodel<- EffFlexi(Eff=c(1.223, 2.513),Effdose=c(25,300),
                    sigma2=c(a=0.1,b=0.1),sigma2betaW=c(a=20,b=50),smooth="RW2",data=data)

## options must be ''McmcOptions' class
options<-McmcOptions(burnin=100,step=2,samples=200)
set.seed(94)
samples<-mcmc(data=data,model=Effmodel,options=options)