filter_signature: Filter the L1000 Signature

In AliSajid/DrugDiscoveryPanCan: Investigate Drug Targets for Kinase Therapies

Description

This function filters the L1000 Signature to a given threshold, identifying up-regulated or down-regulated or both up- and down-regulated genes

Usage

filter_signature(signature, direction = "any", threshold = 0.85)

Arguments

signature	A dataframe with the L1000 signature
direction	Direction to filter to. Must be one of "up", "down" or "any". Defaults to "any"
threshold	A Log Fold-Change Threshold to filter at. Is inclusive and defaults to 0.85

Value

a tibble with the filtered L1000 Signature

Examples

TRUE

AliSajid/DrugDiscoveryPanCan documentation built on Feb. 4, 2021, 6:31 a.m.