germline_filter: Plot expected germline and somatic VAF along with observed...

Description Usage Value

View source: R/germline_filter.R

Description

Plot expected germline and somatic VAF along with observed somatic VAF. And retrieve the the mutational status infered by the method. Variants found to have an observed VAF below 2 standard deviations below the expected value are considered "subclonal". Those falling in the +/- 2 standard deviation range from the expected VAF are annoatated "neutral". Those with VAF greater than 2 starndard deviation above the expected value are annotated as "artifacts".

Usage

1
germline_filter(mat, purity, alpha = 0.05, plot = TRUE, sample)

Value

mat.out


AxelitoMartin/TumorEvolution documentation built on Jan. 12, 2021, 2:43 a.m.