Description Usage Arguments Examples
A function that returns the pathway enrichment score for all perturbed metabolites in a patient's full metabolomic profile.
1 2 | data.getMSEA_Metabolon(met.profile, threshold = 3, type = "zscore",
gene.profile = NULL)
|
met.profile |
- A character vector of a patient's metabolomic profile, including KEGG IDs and the associated z-score or p-value describing the level of the metabolite compared to controls. |
threshold |
- A cutoff to select metabolites with a zscore > threshold or < -1*threshold. |
type |
- Either "p-value" or "z-score". |
gene.profile |
- Default set to NULL, meaning the default enrichment analysis only considers metabolites. However, if you have gene data, too, set this parameter to a character vector of the gene names with found variants in the patient's record. Gene IDs must be converted to Entrez Identifiers. |
1 | pathway.data = data.getMSEA_Metabolon(met.profile, threhold=3, "z-score", NULL)
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