get_emt_score: Calculates Epithelial Mesenchymal transition (EMT) score

Description Usage Arguments Details Value Examples

View source: R/get_emt_score.R

Description

Calculates Epithelial Mesenchymal transition (EMT) score

Usage

1

Arguments

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A numeric data frame or matrix with samples as columns and gene/proteins as rows.

Details

To calculate EMT score, gene expressions in EMT_gene_list are weighted by their sign factor to account for the direction of the effect on EMT (See EMT_gene_list for list of genes and their direction of effect). The EMT_score is defined as mean value of modified expressions. Scores are then mean-centered and normalized by standard deviation based on distribution of scores in all samples.

Value

a dataframe of EMT scores for each sample

Examples

1

Bozorgui/imogene documentation built on Feb. 21, 2022, 11:57 a.m.