group_genes: Group genes with similar expression

In CDecamps/penda: A R package that performs personalized differential analysis of comics data

Group genes with similar expression

Description

This function makes group of genes with similar expression. For each group, the proportion of dysregulated genes in cancer and the extent of variation are computed.

Usage

group_genes(controls, cancer_data, size_grp = 100, quant = 0.05)

Arguments

controls	The matrix of gene expression in controls.
cancer_data	The matrix of gene expression in cases (ex: cancer).
size_grp	The size of the groups of genes.
quant	The quantile of gene expression in control. Cancer genes outside this limit are considered dysregulated.

Value

This function returns a matrix of four columns : Limit min, the first value of the group, Limit max, the last value of the group, Proportion of dysregulation, the proportion of cancer genes outside the quantile limit. Deltas dysregul, a list with all the value of cancer genes - control genes.

CDecamps/penda documentation built on March 29, 2024, 3:26 a.m.