dot-foldChangeNorm: Normalize Intensity based on foldchange

In CeMOS-Mannheim/moleculaR: Spatial Probabilistic Mapping of Metabolite Ensembles in Mass Spectrometry Imaging

Normalize Intensity based on foldchange

Description

This normalizes spectral intensities such that for every spectrum a median fold-change of peak intensities is calculated with reference to the mean spectrum which is then taken as a normalization factor for that particular spectrum.

Usage

.foldChangeNorm(x, meanMethod = "mean")

Arguments

x:	a list of MassPeaks objects.
meanMethod:	see ?MALDIquant::mergeMassPeaks for more info.

Value

Intensity-normalized list of MassPeaks objects.

References

Veselkov, Kirill, et al. "BASIS: High-performance bioinformatics platform for processing of large-scale mass spectrometry imaging data in chemically augmented histology." Scientific reports 8.1 (2018): 1-11.

CeMOS-Mannheim/moleculaR documentation built on April 14, 2025, 8:27 a.m.