In CogDisResLab/KinaseTauScore: Tau Scores For Human Kinases

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KinaseTauScore

KinaseTauScore is a data package that allows access to a curated dataset of phsophorylation profiles of human kinases on the 𝛕-protein in an Alzhemier Disease context. The data is derived from the paper High-content siRNA screening of the kinome identifies kinases involved in Alzheimer's disease-related tau hyperphosphorylation by Azorsa et al^1.

Azorsa DO, Robeson RH, Frost D, et al. High-content siRNA screening of the kinome identifies kinases involved in Alzheimer’s disease-related tau hyperphosphorylation. BMC Genomics. 2010;11(1):25. <doi:10.1186/1471-2164-11-25>

Installation instructions

Get the latest stable R release from CRAN. Then install KinaseTauScore from Bioconductor using the following code:

if (!requireNamespace("BiocManager", quietly = TRUE)) {
    install.packages("BiocManager")
}

BiocManager::install("KinaseTauScore")

And the development version from GitHub with:

BiocManager::install("CogDisResLab/KinaseTauScore")

Citation

Below is the citation output from using citation('KinaseTauScore') in R. Please run this yourself to check for any updates on how to cite KinaseTauScore.

print(citation('KinaseTauScore'), bibtex = TRUE)

Please note that the KinaseTauScore was only made possible thanks to many other R and bioinformatics software authors, which are cited either in the vignettes and/or the paper(s) describing this package.

Code of Conduct

Please note that the KinaseTauScore project is released with a Contributor Code of Conduct. By contributing to this project, you agree to abide by its terms.

Development tools

• Continuous code testing is possible thanks to GitHub actions through r BiocStyle::CRANpkg('usethis'), r BiocStyle::CRANpkg('remotes'), and r BiocStyle::CRANpkg('rcmdcheck') customized to use Bioconductor's docker containers and r BiocStyle::Biocpkg('BiocCheck').
• Code coverage assessment is possible thanks to codecov and r BiocStyle::CRANpkg('covr').
• The documentation website is automatically updated thanks to r BiocStyle::CRANpkg('pkgdown').
• The code is styled automatically thanks to r BiocStyle::CRANpkg('styler').
• The documentation is formatted thanks to r BiocStyle::CRANpkg('devtools') and r BiocStyle::CRANpkg('roxygen2').

For more details, check the dev directory.

This package was developed using r BiocStyle::Biocpkg('biocthis').

CogDisResLab/KinaseTauScore documentation built on June 16, 2022, 6:55 p.m.