hic_example_data: Example HiC dataset

hic_example_dataR Documentation

Example HiC dataset

Description

This dataset contains HiC data from Seitan et al. 2013. The data was analysed using HOMER (Heinz et al. 2010) at a resolution of 100kb to find significant interactions. This example dataset has been filtered to retain only interactions on chromosomes 14 and 15 with a FDR < 0.1. The data has also been annotated for overlaps with Refseq promoters. See the HiC analysis vignette (vignettes(GenomicInteractions)) for more information on how this dataset was created.

Usage

data(hic_example_data)

Format

A GenomicInteractions object with length 8171.

Value

GenomicInteractions object

References

Seitan, V. C. et al. Cohesin-based chromatin interactions enable regulated gene expression within pre-existing architectural compartments. Genome Res. 23, 2066-77 (2013).

Heinz S, Benner C, Spann N, Bertolino E et al. Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities. Mol Cell 2010 May 28;38(4):576-589.


ComputationalRegulatoryGenomicsICL/GenomicInteractions documentation built on April 16, 2022, 4:09 a.m.