likelihood_dual: Calculate likelihood curve of frequency estimates for a...
In EdwardSLee/alphabetr: Algorithms for High-Throughput Sequencing of Antigen-Specific T Cells

Calculate likelihood curve of frequency estimates for a dual-alpha or dual-beta TCR clone

1	likelihood_dual(est, err, numb_wells, numb_cells, numb_sample)

`est`	Clonal frequency estimate
`err`	Mean drop error rate
`numb_wells`	A vector with the number of wells with the distinct sample sizes
`numb_cells`	A vector of the distinct sample sizes, i.e. the number of cells per well
`numb_sample`	A vector with the number of wells of the sample size of the same position of `numb_cells` that contains both alpha and the beta chain of the clone (for dual-alpha clones) or both beta and the alpha chain of the clone (for dual-beta clones)

A numeric with the negative log likelihood

EdwardSLee/alphabetr documentation built on May 6, 2019, 3:12 p.m.

EdwardSLee/alphabetr index

README.md

Note that we can't provide technical support on individual packages. You should contact the package authors for that.

Description