correctImpurities: Performs purity correction on generic TMT data.

In GoldfarbLab/TMTPurityCorrection: Corrects TMT reporter intensities for TMT impurities

Description

Performs purity correction on generic TMT data.

Usage

correctImpurities(
  data,
  impurities,
  noise,
  method = c("NNLS", "OLS"),
  noise.replacement.method = c("pre", "post", "none"),
  remain.missing = T
)

Arguments

data	data frame of uncorrected TMT intensities.
impurities	data frame of impurities for a specific lot
noise	optional data frame of TMT noiseband values. Must line up row by row with data
method	purity correction method. Options = "NNLS" and "OLS"
noise.replacement.method	should the noiseband replace missing values before or after correction. Options = "pre", "post", "none"
remain.missing	should missing values be set to 0 (missing) after correction or not. Only used if not doing noiseband imputation. True or False

GoldfarbLab/TMTPurityCorrection documentation built on Jan. 7, 2022, 2:01 p.m.