IDDI-BE/PhIIdesign: Sample Size Calculation for Phase II Designs

Sample size calculations for designs of Phase II clinical trials. In particular techniques described in the following papers: 'One-sample Multiple Testing Procedure for Phase II Clinical Trials' by Fleming (1982) <doi:10.2307/2530297>. 'A Three-Outcome Design for Phase II Clinical Trials' by Sargent et al (2001) <doi:10.1016/s0197-2456(00)00115-x>. 'Optimal Two-Stage Designs for Phase II Clinical Trials' by Simon et al (1989) <doi:10.1016/0197-2456(89)90015-9>. 'Admissible Two-Stage Designs for Phase II Cancer Clinical Trials' by Jung et al (2004) <doi:10.1002/sim.1600>.

install.packages("remotes")
remotes::install_github("IDDI-BE/PhIIdesign")