Description Usage Arguments References Examples
Plots the probability of rejecting H0 ('Positive result') and rejecting Ha
('Negative result') for different true response binomial parameters
if the input is an object returned by fleming1stage
, simon2stage
,
simon2stage
, sargent1stage
or sargent2stage
, interactively choose
the design number
1 2 3 4 5 6 7 8 9 |
x |
an object returned by |
design_nr |
design_nr returned by |
main |
title of the graph, passed on to |
xlab |
x-axis label of the graph, passed on to |
grid |
add grid to plot ("Y" or "N") |
ylab |
y-axis label of the graph, passed on to |
... |
other arguments passed on to |
Sargent DJ, Chan V, Goldberg RM. A three-outcome design for phase II clinical
trials. Control Clin Trials. 2001;22(2):117-125. doi:10.1016/s0197-2456(00)00115-x
Simon R. Optimal two-Stage Designs for Phase II Clinical Trials.
Control Clin Trials. 1989;10:1-10
1 2 3 4 5 6 7 8 9 10 11 12 13 14 | fleming1 <- fleming1stage(p0 = 0.45, pa = 0.7, alpha = 0.05, beta = 0.2)
plotPhII(fleming1)
simon2<- simon2stage(p0 = 0.1, pa = 0.3, alpha = 0.05, beta = 0.2,
eps = 0.005, N_min = 1, N_max = 50)
plotPhII(simon2)
sargent1 <- sargent1stage(p0 = 0.2, pa = 0.35, alpha = 0.1, beta = 0.1, eta = 0.8, pi = 0.8,
eps = 0.005, N_min = 35, N_max = 50)
plotPhII(sargent1)
sargent2 <- sargent2stage(p0 = 0.1, pa = 0.3, alpha = 0.05, beta = 0.1,
eta = 0.8, pi = 0.8,
eps = 0.005, N_min = 15, N_max = 30)
plotPhII(sargent2,design_nr=1)
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