merge_omics: merge.omics merges proteomics, genomics, and ligandomics data...

Description Usage Arguments

Description

merge.omics merges proteomics, genomics, and ligandomics data of an experiment

Usage

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merge_omics(selected.cell.line, dbfile, is_perturbation = F,
  condition = NULL, additionalGrepCondition = "", minReplicates = 1,
  allele.predictions = NULL, allele.predictor = "ic50",
  nM.threshold = 1000, saveAllResults = F, GOcategories = NULL)

Arguments

selected.cell.line

cell line to integrate data

dbfile

Uniprot database filename (NOT in fasta format! Use the xls format)

is_perturbation

indicates if the experiment is a perturbation experiment

condition

in case of a perturbation, this indicates which condition you want to use

minReplicates

for ligandomics data, the minimum number of biological replicates required to validate a ligand

allele.predictions

data frame containing allele predictions for the ligands. If NULL, they will be estimated

allele.predictor

c("rank", "ic50") predictor to be used.

nM.threshold

minimum nanomolar threshold for validating the predictions

saveAllResults

save allele predictions and merged omics table at the working directory

GOcategories

a string vector containing gene ontology categories you want to include as separate variables


IFIproteomics/E2Predictor documentation built on May 8, 2019, 10:54 a.m.