merge.omics merges proteomics, genomics, and ligandomics data of an experiment
1 2 3 4 | merge_omics(selected.cell.line, dbfile, is_perturbation = F,
condition = NULL, additionalGrepCondition = "", minReplicates = 1,
allele.predictions = NULL, allele.predictor = "ic50",
nM.threshold = 1000, saveAllResults = F, GOcategories = NULL)
|
selected.cell.line |
cell line to integrate data |
dbfile |
Uniprot database filename (NOT in fasta format! Use the xls format) |
is_perturbation |
indicates if the experiment is a perturbation experiment |
condition |
in case of a perturbation, this indicates which condition you want to use |
minReplicates |
for ligandomics data, the minimum number of biological replicates required to validate a ligand |
allele.predictions |
data frame containing allele predictions for the ligands. If NULL, they will be estimated |
allele.predictor |
c("rank", "ic50") predictor to be used. |
nM.threshold |
minimum nanomolar threshold for validating the predictions |
saveAllResults |
save allele predictions and merged omics table at the working directory |
GOcategories |
a string vector containing gene ontology categories you want to include as separate variables |
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