InfOmics/LErNet: LErNet: characterization of lncRNAs via context-aware network expansion and enrichment analysis
Long non-coding RNAs (lncRNA) have recently acquired a boost of interest for their implication in several biological conditions. However, many of these elements are not yet annotate. LErNet is focused on a new network analysis method for annotating lncRNAs and guide the enrichment analysis. The core is a network expansion algorithm that aims to enrich the context of lncRNAs. The context is constructed by integrating the genes encoding proteins that are found next to the non-coding elements at both the genome and the system level. The pipeline is particularly useful in situations where the functions of discovered lncRNAs are not yet known.
Getting started
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Package details |
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| Author | Vincenzo Bonnici, Michele Marchi, Nipuli Fernando, Rosalba Giugno |
| Maintainer | Vincenzo Bonnici <vincenzo.bonnici@univr.it> |
| License | MIT + file LICENSE |
| Version | 1.0 |
| Package repository | View on GitHub |
| Installation |
Install the latest version of this package by entering the following in R:
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