expand_seeds: Expansion of the seed network

Description Usage Arguments Value

View source: R/LErNet.R

Description

Expands with connectors the network formed by seed proteins, that are the produtcs of the genes in the genomic context and in the interaction context, by the expansion algorithm. Connectors are neighbors of selected proteins in the input PPI network.

Usage

1
expand_seeds(seeds, ppi_network, de_proteins = NULL)

Arguments

seeds

a list produced by get_genomic_context and search_in_arenaidb

ppi_network

a two column data.frame representing PPI network edges (see also get_stringdb )

de_proteins

a vector of stricted proteins. If empty, the complete set of neighbors is extracted otherwise only pcgenes in this set are taken into account.

Value

a list

out_components

a list of connected components of the resultant expanded network. Each compoent is a list of proteins.


InfOmics/LErNet documentation built on April 10, 2021, 4:49 p.m.