View source: R/apply_duration_scale.R
apply_duration_scale | R Documentation |
E.g. see Centanni et al. Clin Pharmacokinet 2024. An estimated scaling factor for the length of the infusion was applied there in a model for vincristine. This is likely most relevant for very short infusions.
apply_duration_scale(
regimen,
duration_scale = NULL,
parameters = NULL,
cmt_mapping = NULL
)
regimen |
PKPDsim regimen |
duration_scale |
infusion length scale. |
parameters |
parameter list, required if the duration scale is specified as a parameter. |
cmt_mapping |
map of administration types to compartments, e.g. 'list("oral" = 1, "infusion" = 2, "bolus" = 2)'. |
Implementation is similar to handling of 'lagtime', i.e. the regimen that is the input for the simulation function is updated.
Original regimen with infusion lengths scaled by a factor
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