View source: R/calculate_parameters.R
calculate_parameters | R Documentation |
This is a convenience function for PKPDsim users, it is not used inside the 'sim_ode()“ function in any way. This function is useful for converting from an estimated parameter to actual parameter, e.g. when clearance is specified as 'CLi = CL * (WT/70) * (1/CR)' it can be used to calculate 'CLi' without having to write that function a second time in R.
calculate_parameters(
ode = NULL,
parameters = NULL,
covariates = NULL,
include_parameters = TRUE,
include_variables = TRUE,
regimen = NULL,
t_obs = NULL,
...
)
ode |
PKPDsim model object |
parameters |
parameter list |
covariates |
covariate list. Make sure to include covariates at the right time point, since only last observed covariate values are used. |
include_parameters |
boolean, include parameters? |
include_variables |
boolean, include variables? |
regimen |
optional, provide a 'regimen' object for the computation of the effective parameters. This is only relevant for models for which parameters depend on the dose or administration type, which is rare. |
t_obs |
optional, provide timepoint(s) at which to computate effective parameters. This is only relevant for models with time-varying fixed-effects. If unspecified, will evaluate parameters at 't=0'. |
... |
arguments to pass on to simulation function |
List of model-specific variables
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