ssmdC.homoVAR.frame.fn: calculate the critical value of SSMD between a positive...

Description Usage Arguments Value Author(s) Examples

View source: R/ssmdC.homoVAR.frame.fn.R

Description

A function to calculate the critical value of SSMD between a positive control and a negative reference in a data frame for an HTS study

Usage

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ssmdC.homoVAR.frame.fn(
  dataIn.df,
  negREF = "Sample",
  positiveCTRL = "positive control",
  pREFtrim = 0,
  Alpha = 0.05,
  Beta = 3
)

Arguments

dataIn.df

a data frame with plate ID (or name), well usage and intensity

negREF

name of wells to be used as a negative reference

positiveCTRL

name of wells to be used as a positive control

pREFtrim

the total portion of data to be trimmed in the negative reference

Alpha

specify the significant level

Beta

the population value of SSMD

Value

a matrix containing estimated SSMD value and variance for each plate

Author(s)

Xiaohua Douglas Zhang and Dandan Wang 07/2020

Examples

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 data("data.CVB3CRISPR", package="qcSSMD")
  data.df = dataCVB3.df
  ssmdC.homoVAR.frame.fn(dataIn.df=data.df, negREF="Sample", positiveCTRL="Positive Control",
                         pREFtrim=0.05, Alpha=0.05, Beta=3)

Karena6688/qcSSMD documentation built on July 23, 2020, 9:50 a.m.