ssmdEst.homoVAR.frame.fn: calculate UMVUE estimate of SSMD between a positive control...

In Karena6688/qcSSMD: calcuate SSMD for quality control

Description

A function to calculate UMVUE estimate of SSMD between a positive control and a negative reference in a data frame for an HTS study

Usage

ssmdEst.homoVAR.frame.fn(
  dataIn.df,
  negREF = "Sample",
  positiveCTRL = "positive control",
  pREFtrim = 0,
  approx = FALSE,
  method = "UMVUE"
)

Arguments

dataIn.df	a data frame with plate ID (or name), well usage and intensity
negREF	name of wells to be used as a negative reference
positiveCTRL	name of wells to be used as a positive control
pREFtrim	the total portion of data to be trimmed in the negative reference
approx	approx=TRUE, indicating the use of approximation for the coefficient in the UMVUE estimate of SSMD
method	specify the method for estimating SSMD. It must be either 'UMVUE', 'MLE' or'MM'. "

Value

a matrix containing estimated SSMD value and variance for each plate

Author(s)

Xiaohua Douglas Zhang and Dandan Wang 07/2020

Examples

 data("data.CVB3CRISPR", package="qcSSMD")
  data.df = dataCVB3.df
  ssmdEst.homoVAR.frame.fn(dataIn.df=data.df, negREF="Sample", positiveCTRL="Positive Control",
                         pREFtrim=0.05, approx=FALSE, method="UMVUE")

Karena6688/qcSSMD documentation built on July 23, 2020, 9:50 a.m.