This package finds and filters artificial chimeric reads specifically generated in next-generation sequencing (NGS) process of formalin-fixed paraffin-embedded (FFPE) tissues. These artificial chimeric reads can lead to a large number of false positive structural variation (SV) calls. The required input is an indexed BAM file of a FFPE sample.
Package details |
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Bioconductor views | Alignment Preprocessing QualityControl Sequencing StructuralVariation |
Maintainer | |
License | LGPL-3 |
Version | 1.1.2 |
Package repository | View on GitHub |
Installation |
Install the latest version of this package by entering the following in R:
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