This package finds and filters artificial chimeric reads specifically generated in next-generation sequencing (NGS) process of formalin-fixed paraffin-embedded (FFPE) tissues. These artificial chimeric reads can lead to a large number of false positive structural variation (SV) calls. The required input is an indexed BAM file of a FFPE sample.
|Bioconductor views||Alignment Preprocessing QualityControl Sequencing StructuralVariation|
|Package repository||View on GitHub|
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