LanyingWei/SimFFPE: NGS Read Simulator for FFPE Tissue
The NGS (Next-Generation Sequencing) reads from FFPE (Formalin-Fixed Paraffin-Embedded) samples contain numerous artifact chimeric reads (ACRS), which can lead to false positive structural variant calls. These ACRs are derived from the combination of two single-stranded DNA (ss-DNA) fragments with short reverse complementary regions (SRCRs). This package simulates these artifact chimeric reads as well as normal reads for FFPE samples on the whole genome / several chromosomes / large regions.
Getting started
Browse package contents
Package details |
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| Bioconductor views | Alignment DataImport MultipleComparison SequenceMatching Sequencing |
| Maintainer | |
| License | LGPL-3 |
| Version | 1.3.2 |
| Package repository | View on GitHub |
| Installation |
Install the latest version of this package by entering the following in R:
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