patlist_sim: A list of patient information

In LuZhangstat/Phase1Mayo: Personalized Repeated Measurement Design for Phase I Clinical Trials

Description

The data "patlist_sim" is a trial generated by "SimPRMD". The model utilized for generating trial is a 3-stage model with individualized dose modification. The MTD = 4 and the MED = 1 since the dose-efficacy pattern when generating the trial was set to be flat. The dose-toxicity trend and efficacy-cycle trend are flat. There are in total 12 cohorts with 3 patients in each cohort. This also serves as an example of the input data of function RunPRMD.

Usage

patlist_sim

Format

An object of class list of length 6.

Value

PatID	denotes the patient ID where the elements are specified by cohort and subject number. For example, "cohort2subject3" denotes the third subject in the second cohort
dose	records the dose assigned for each patient on different cycles
cycle	shows the treatment cycle
nTTP	records th corresponding nTTP score.
dlt	indicates whether a DLT event is observed or not?
efficacy	provides the continuous efficacy for each cycle. The range of efficacy measure is (0, 1).

LuZhangstat/Phase1Mayo documentation built on March 16, 2020, 1:32 a.m.