gwas_catalog: Data frame of GWAS significant SNPs obtained from the EBI...

Description Usage Format Source

Description

Downloaded from EBI on 18/03/2016. Standardised to make units as consistent as possible, trait names, obtain gene annotation. Effect sizes and standard errors are all converted to log odds ratio for binary traits. Ensembl used to identify alleles and effect allele frequency where missing.

Usage

1

Format

A data frame with 22783 rows and 17 columns

Phenotype_simple

Simple phenotype name

Phenotype

This phenotype also has units and details if they are necessary to distinguish different studies

Phenotype_info

Phenotype_info

PubmedID

PubmedID

Author

Author

Year

Year

SNP

SNP

chr

chr

bp_ens_GRCh38

bp_ens_GRCh38

Region

Region

gene

gene

Gene_ens

Gene_ens

effect_allele

effect_allele

other_allele

other_allele

beta

beta

se

se

pval

pval

units

units

eaf

eaf

date_added_to_MRBASE

Date GWAS catalog downloaded and added to MR-Base

Initial_sample_description

Sample size and ancestry description for stage 1 of GWAS (summing across multiple Stage 1 populations, if applicable)

Replication_sample_description

Sample size and ancestry description for subsequent replication(s) (summing across multiple populations, if applicable)

MAPPED_TRAIT_EFO_URI

URI of the EFO trait

MAPPED_TRAIT_EFO

Mapped Experimental Factor Ontology trait for this study

STUDY.ACCESSION

Accession ID allocated to a GWAS Catalog study

Source

https://scmv-ieugit.epi.bris.ac.uk/gh13047/gwas_catalog_standardisation


MRCIEU/MRInstruments documentation built on June 24, 2020, 9:34 a.m.